| 105 N 2nd St | YMCA (Schwartz 145) |
| 128 N 2nd St | First Church of Christ Scientist (Schwartz 114) |
| 242 N 2nd St | 242 N 2nd St:Mrs. Sheehan House |
| 303 N 2nd St | George Helvey Residence |
| 308 N 2nd St | John Holbrock House |
| 315 N 2nd St | John Frechtling House |
| 319 N 2nd St | Henry Frechtling House |
| 327 N 2nd St | Benninghofen House (Schwartz 163) |
| 328 N 2nd St | Peter Hunzer House |
| 338-340 N 2nd St | Alstatter House |
| 341-343 N 2nd St | Long & Alstatter House (Schwartz 162) |
| 348-350 N 2nd St | Young/Neff House |
| 402 N 2nd St | Edward Hibney House |
| 406 N 2nd St | John Hurin House |
| 417 N 2nd St | William Hurin House |
| 419-421 N 2nd St | George Schwab House |
| 442 N 2nd St | Sarah Mitchell House |
| 6 S 2nd St | Society Bank Building: Rentschler Building (Schwartz 35) (Schwartz 150) |
| 24 2nd St | Denham-Lashhorn-Wiseman Company |
| 119 S 2nd St | Butler County Welfare Dept. - Butler Co. Soldiers' Relief Com. : Moebus Building |
| 120 S 2nd St | Grevey, Green, and Garretson/ Security Pacific Finance: Mary Tule Boardinghouse / Hossfeld Building (Schwartz 23) |
| 319 S 2nd St | J&B Furniture & Appliance Inc. : Miami Motor Car Co. (Schwartz 21) |
| 327 S 2nd St | Loyal Order of Moose Hall: Moose Palm Garden/ Moose Auditorium & Moose Bowling Alley |
| 421 S 2nd St | Allen Rents/ Cappy's Shoe Service: Kiefler Shoes/ Pater Shoes |
| 439 S 2nd St | Labor Temple |
| 507 S 2nd St | Alfred F. Holbrock Residence |
| 542 S 2nd St | Edward G. Bruck Residence |
| 548 S 2nd St | Schumaker Residence |
| 724 S 2nd St | Smith-Wheeler House |
| 926 S 2nd St | Headstart Program: Notre Dame High School/Badin High School: Notre Dame Academy - Sisters of Notre Dame |
| 1002 S 2nd St | Benz-Mitchell-Thomason House |
| 2nd & Owen | Ice Storage House |
| S 2nd St & Central Ave | Goodwill Store: Harrison Elementary School |
| S 2nd & Hanover | St. Joseph School |
| S 2nd & Washington | St. Joseph's Church: St. Joseph's Kirche (Schwartz 108) |
| NEC 2nd St & Walnut St | Park Lounge |
|